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目的研究及分析2012年~2014年本院药物不良反应发生情况。方法选取2012年1~12月本院发生药物不良反应的95例患者为A组,2013年1~12月的98例患者为B组,2014年1~12月的96例患者为C组,然后将三组不良反应种类及药物应用种类进行分别统计及比较。结果三组患者的不良反应均以皮肤方面的不良反应为主,明显高于其他不良反应,抗菌药物导致的不良反应明显高于其他药物,且C组的抗菌药物导致的不良反应明显低于A组及B组,P均<0.05,均有显著性差异。结论 2012年~2014年本院药物不良反应发生率较高,抗菌药物导致的不良反应及皮肤方面的不良反应较高,抗菌药物不良反应得到有效控制,但是仍有较大的降低空间。
Objective To study and analyze the incidence of adverse drug reactions in our hospital from 2012 to 2014. Methods Ninety-five patients with adverse drug reactions in our hospital from January to December in 2012 were selected as Group A, 98 patients in Group B from January to December 2013, 96 patients in Group C from January to December 2014, Then three types of adverse reactions and types of drug use were statistically and compared. Results The adverse reactions in all three groups were mainly skin side effects, which were significantly higher than those of other adverse reactions. The adverse reactions caused by antimicrobial agents were significantly higher than those of other drugs. The side effects of antimicrobial drugs in group C were significantly lower than those of A Group and group B, P <0.05, there was a significant difference. Conclusions The incidence of adverse drug reactions in our hospital from 2012 to 2014 is high. The adverse reactions caused by antibiotics and adverse reactions in skin are high. The adverse reactions of antibacterials are effectively controlled, but there is still much room for reduction.