Phase Ⅱ enzymes activity induced by curcumin accompanying translocation of Nrf2 and activation of AR

• 作 者: YE She-fang WU Yi-hui ZHONG Li
• 机 构: Keylaboratoryofbiomedicalengineering
• 出 处: 毒理学杂志
• 发表日期: 2007年4期
• 关键词: 姜黄色素 NRF2 相位Ⅱ酶 酶活性 易位 激活 谷胱甘肽S转移酶 辅酶II eurcumin phage Ⅱ enzyme Nrf2 ehemop

Aim To investigate the effect of curcumin on induction of glutathione S-transferases (GST), NADP(H):quinone oxidoreductase (NQO) and explore their possible molecular mechanism. Methods The activity of GST, NQO and cellular reduced glutathione (GSH) conten