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喉癌是上呼吸道常见的恶性肿瘤之一，它的发生发展与某些癌基因的激活和抑癌基因的失活有关。ｐ５３和ｐ２１蛋白是常见的抑癌基因和癌基因的表达产物，ＰＣＮＡ为衡量肿瘤细胞增殖状态的标志之一。本文采用免疫组化法联合检测ＰＣＮＡ、ｐ５３、ｐ２１在喉癌组织中的表达水平
Laryngeal cancer is one of the most common malignant tumors in the upper respiratory tract. Its occurrence and development are related to the activation of some oncogenes and the inactivation of tumor suppressor genes. p53 and p21 proteins are common expression products of tumor suppressor genes and oncogenes, and PCNA is one of the markers for measuring the proliferation status of tumor cells. In this paper, immunohistochemistry combined detection of PCNA, p53, p21 in laryngeal cancer tissue expression levels