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膀胱原发性血管肉瘤非常罕见,文献中大约有30例报道;而上皮样形态的血管肉瘤更加罕见,文献报道仅有1例。作者收集1998—2014年期间外科病理档案中的9例膀胱上皮样血管肉瘤(EA),观察其组织病理学特征并进行临床随访。患者中位年龄65岁(范围9~95岁),男∶女=8∶1。9例临床表现均为血尿和膀胱肿块,6例有骨盆放射治疗史(5例前列腺癌,1例宫颈癌)。从放射治疗到诊断EA的时间为6~15年。
Bladder primary angiosarcoma is very rare, about 30 cases reported in the literature; and epithelial-like angiosarcoma is even more rare, only one reported in the literature. The authors collected 9 cases of bladder epithelioid-like angiosarcoma (EA) in the surgical pathology archives from 1998 to 2014 and observed their histopathological features and clinical follow-up. The median age was 65 years (range, 9 to 95 years), male and female = 8: 1. The clinical manifestations of 9 patients were all hematuria and bladder mass. Six patients had history of pelvic radiotherapy (5 cases of prostate cancer and 1 case of cervical cancer ). The time from radiotherapy to diagnosis of EA is 6 to 15 years.