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目的:分析研究胃癌术前营养支持与肿瘤生长之间的关系。结果:选取2011年2月-2014年3月云南省文山州人民医院收治的21例胃癌患者,对21例患者在手术前7 d采取普通饮食联合静脉营养支持,对其营养支持与肿瘤生长之间的关系给予分析研究。结果:静脉营养支持以后,胃癌细胞的G0/G1%明显下降,差异具有统计学意义(P<0.05),S-G2-M%显著增加,差异具有统计学意义(P<0.05);正常胃粘膜细胞没有类似变化。另外,静脉营养支持以后自然杀伤细胞(NKC)活性有明显增加,但是以CD4+增加最为明显,差异具有统计学意义(P<0.05)。结论:胃癌手术之前采取静脉营养支持,可以使患者免疫力得到明显改善,但是会刺激肿瘤细胞生长。
Objective: To analyze the relationship between preoperative nutritional support and tumor growth in gastric cancer. Results: Twenty-one patients with gastric cancer admitted from February 2011 to March 2014 in Wenshan Prefecture People’s Hospital of Yunnan Province were enrolled. Twenty-one patients underwent routine diet and parenteral nutrition support on the 7th day before operation. The nutritional support and tumor growth The relationship between the analysis given. Results: After the intravenous nutrition support, the G0 / G1% of gastric cancer cells was significantly decreased, the difference was statistically significant (P <0.05), S-G2-M% significantly increased, the difference was statistically significant (P < Mucosal cells did not change similarly. In addition, natural killer cell (NKC) activity was significantly increased after intravenous nutritional support, but the most obvious increase was CD4 +, the difference was statistically significant (P <0.05). CONCLUSIONS: The use of parenteral nutrition support before gastric cancer surgery can significantly improve the patient’s immunity, but it can stimulate tumor cell growth.