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目的:研究活脑灵治疗对脑梗死后记忆障碍患者记忆功能、脑血流量、脑电图等的影响。方法:脑梗死后记忆障碍患者72例,随机分为研究组(38例)和对照组(34例),分别给予活脑灵与胞磷胆碱静脉滴注治疗,1次/d,共4周。治疗前后记忆测定及经颅多普勒(TCD)、脑电图检查。结果:研究组治疗后临床记忆量表中指向记忆(12.85±6.13)分、图像自由回忆(14.67±8.02)分、无意义图像再认(18.61±3.16)分、人像特点联想回忆(17.79±5.12)分、MQ(80.2±12.1)分,Wechsler积分中的顺序(5.68±0.16)分、倒序(6.37±0.18)分较对照组和治疗前明显改善(t=9.84～14.3,P<0.01)。治疗前两组脑血流学指标差异无显著性意义,治疗后研究组脑大脑中动脉犤左:(63.81±13.12)cm/s,右:(60.61±10.23)cm/s犦、基底动脉犤(42.67±8.02)cm/s犦的平均血流速度及脉动指数与对照组比较显著改善(t=6.8～11.3,P<0.05或0.01)。结论:活脑灵治疗可提高脑梗死后记忆障碍患者的脑血流量,改善患者的记忆能力。
Objective: To study the effects of live brain-Nourishing on memory function, cerebral blood flow and electroencephalogram in patients with memory impairment after cerebral infarction. Methods: Seventy-two patients with memory impairment after cerebral infarction were randomly divided into study group (n = 38) and control group (n = 34), treated with intravenous injection of naloxone and citicoline intravenously once daily for 4 days week. Before and after treatment memory determination and transcranial Doppler (TCD), EEG. Results: The memory of the study group was 12.85 ± 6.13, 14.67 ± 8.02, 18.61 ± 3.16, 17.79 ± 5.12, respectively ), MQ (80.2 ± 12.1), Wechsler integral (5.68 ± 0.16), and reverse order (6.37 ± 0.18) compared with the control group and before treatment (t = 9.84-14.3, P <0.01). There was no significant difference in cerebral hemorheology between the two groups before treatment. After treatment, the left middle cerebral artery of the study group was (63.81 ± 13.12) cm / s, right: (60.61 ± 10.23) cm / s 犦, basilar artery 犤(42.67 ± 8.02) cm / s 犦, mean blood flow velocity and pulse index were significantly improved compared with the control group (t = 6.8 ~ 11.3, P <0.05 or 0.01). Conclusion: Living brain treatment can improve cerebral blood flow in patients with memory impairment after cerebral infarction and improve the memory ability of patients.