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目的探讨卡前列素氨丁三醇防治高危产妇剖宫产术中及术后出血的临床效果。方法选取2014年1月至2015年1月医院收治的的90例行剖宫术的高危产妇作为研究对象,按随机数字表法将其分为试验组与对照组,每组45例。对照组应用缩宫素注射治疗,试验组应用卡前列素氨丁三醇治疗,比较两组产妇止血效果。结果试验组产妇术中出血量与产后2 h、24 h出血量均明显低于对照组,手术时间显著短于对照组,差异均有统计学意义(均P<0.05);试验组产妇成功止血时间为(19±11)min,明显短于对照组的(40±12)min,差异有统计学意义(t=8.9189,P<0.05);试验组产妇对于止血的满意度评分为(98.8±2.5)分,明显高于对照组的(85.6±1.2)分,差异有统计学意义(t=313.0654,P<0.05)。结论高危产妇剖宫产术中预防性的使用卡前列素氨丁三醇,能够有效预防产妇因高危因素而引发的产后出血,效果显著,且安全性较高。
Objective To investigate the clinical effect of carboprost tromethamine on prevention and treatment of high risk maternal cesarean section and postoperative bleeding. Methods A total of 90 high risk pregnant women who underwent cesarean section in our hospital from January 2014 to January 2015 were selected as research subjects and divided into experimental group and control group according to random number table method, with 45 cases in each group. The control group was treated with oxytocin injection. The test group was treated with carboprost tromethamine, and the bleeding effect of the two groups was compared. Results The bleeding volume of the experimental group was significantly lower than that of the control group at 2 h and 24 h postoperatively, and the operation time was significantly shorter than that of the control group (all P <0.05). The maternal successful hemostasis (19 ± 11) min, which was significantly shorter than that of the control group (40 ± 12) min, the difference was statistically significant (t = 8.9189, P <0.05) 2.5), which was significantly higher than that of the control group (85.6 ± 1.2), the difference was statistically significant (t = 313.0654, P <0.05). Conclusions The prophylactic use of carboprost in caesarean section in high-risk maternal women can effectively prevent maternal postpartum hemorrhage caused by high-risk factors and has a significant effect and high safety.