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胆红素是血红素的代谢产物,被认为是一种有害物质,但胆红素具有抗氧化、抗炎、抗动脉粥样硬化等作用。血浆胆红素水平与卒中风险因素呈负相关,对卒中风险有较好的预测作用。胆红素水平与急性脑梗死严重性呈正相关,通过提高体内胆红素水平来预防和治疗心、脑血管疾病尤其是缺血性脑血管病有重要意义。本文就胆红素与脑血管疾病关系的研究进展作一综述。
Bilirubin is a heme metabolite, is considered a harmful substance, but bilirubin has anti-oxidation, anti-inflammatory, anti-atherosclerotic effect. Plasma bilirubin levels were negatively correlated with stroke risk factors and had a better predictive value for stroke risk. Bilirubin levels and the severity of acute cerebral infarction was positively correlated, by increasing the level of bilirubin in the body to prevent and treat heart and cerebrovascular diseases, especially ischemic cerebrovascular disease is of great significance. This article reviews the research progress of the relationship between bilirubin and cerebrovascular diseases.