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目的了解郑州市二七区侯寨乡3~6岁儿童接种乙肝疫苗后抗体水平。方法应用ELISA方法,对来我院体检的2004-2007年出生的接种乙型肝炎疫苗的儿童检测血清HBsAg和抗-HBs的阳性率。结果共检测3~6岁儿童651人,其中HBsAg阳性人数4人,阳性率为0.61%,抗-HBs阳性人数397人,阳性率为60.98%。男女抗体阳性率之间差异有统计学意义(P<0.05)。结论乙肝疫苗是预防肝炎的有效措施,应根据抗-HBs检测结果,及时加强补种。男性抗-HBs阳性率低于女性,应加大免疫剂量并及时补种乙肝疫苗。
Objective To understand the antibody level of hepatitis B vaccine in 3-6-year-old children in Houzhai Township, Erqi District, Zhengzhou City. Methods The positive rate of serum HBsAg and anti-HBs in children vaccinated with hepatitis B from 2004 to 2007 in our hospital for physical examination was measured by ELISA. Results A total of 651 children aged 3 to 6 years were tested, including 4 HBsAg positive patients, the positive rate was 0.61% and the anti-HBs positive number was 397, the positive rate was 60.98%. There was a significant difference between male and female antibody positive rate (P <0.05). Conclusion Hepatitis B vaccine is an effective measure to prevent hepatitis. According to the results of anti-HBs test, the vaccine should be strengthened in time. The positive rate of anti-HBs in males is lower than that in females, the dosage of immunization should be increased and the hepatitis B vaccine should be replanted in time.