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催产素对子宫有高度选择性的作用。小剂量能激起并增强妊娠末期子宫的节律性收缩,大的剂量(约10个国际单位)则引起强直性收缩。肌肉注射如药量掌握不好,可能造成子宫呈葫芦形收缩,胎盘箝闭,甚至子宫破裂等严重后果。已往用该药由静脉滴入催产,但此法在广大农村家庭接生中使用不便,因此我们改用催产素滴鼻催产,效果较好。鼻粘膜有丰富的毛细血管,催产素滴入鼻腔后通过渗透作用被鼻粘膜吸收,进入机体循环起到催产作用。
Oxytocin has a highly selective effect on the uterus. Small doses can evoke and enhance rhythmic contractions of the uterus during late pregnancy, and large doses (about 10 international units) cause tonic contractions. Intramuscular injections, such as dose control is not good, may result in a gourd-shaped uterus contraction, placental clamp, or even rupture of the uterus and other serious consequences. The drug has been used by the intravenous drip oxytocin, but this method inconvenience in the majority of rural family births, so we use oxytocin drip nasal oxytocin, the effect is better. Nasal mucosa is rich in capillaries, oxytocin into the nasal cavity by nasal absorption by infiltration, into the body circulation to play an oxytocin role.