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免疫学研究已经发现几种人类肿瘤相关抗原。了解最清楚的是癌胚抗原(CEA)及甲胎蛋白(aFP),二者存在于胚胎组织中。Yachi 等(1968)将已吸收的异种抗血清用双向扩散法,在人支气管癌盐水提取物中,至少发现两种肿瘤相关抗原,二者均溶于50%饱和硫酸铵液中,但其分子大小不同。较小的一种抗原(7 S)不仅与肺癌有关,并与消化道及肾肿瘤有关。在免疫电泳上,当 PH 8.6时,它在α-β区
Immunological studies have identified several human tumor-associated antigens. What is most clear is the carcinoembryonic antigen (CEA) and the alpha-fetoprotein (aFP), both present in the embryonic tissue. Yachi et al. (1968) found that at least two tumor-associated antigens were found in the human bronchial carcinoma saline extract, both of which were dissolved in 50% saturated ammonium sulfate solution by a two-way diffusion method, but their molecular Different size. The smaller one antigen (7 S) is not only associated with lung cancer, but also with the digestive tract and kidney tumors. On immunoelectrophoresis, it is in the alpha-beta region at pH 8.6