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目的研究腔隙性脑梗死患者血清维生素B12的检测结果以及检测意义。方法 37例腔隙性脑梗死患者为研究组,同期接受健康体检的37例正常人为对照组,对比分析两组血清维生素B12水平。结果研究组患者的血清维生素B12水平明显低于对照组,其中研究组重型腔隙性脑梗死患者血清维生素B12水平明显低于轻中型,组间比较差异有统计学意义(P<0.05)。结论经检测认为血清维生素B12水平下降是诱发腔隙性脑梗死的主要原因,控制患者饮食,使患者摄入足量的维生素B12,可有效防止腔隙性脑梗死疾病发生,显著提高患者生活质量。
Objective To study the detection of serum vitamin B12 in patients with lacunar infarction and its significance. Methods Thirty-seven patients with lacunar infarction were selected as study group and 37 normal subjects undergoing physical examination during the same period as control group. The levels of serum vitamin B12 were compared between the two groups. Results The level of serum vitamin B12 in the study group was significantly lower than that in the control group. The level of serum vitamin B12 in the study group was significantly lower than that in the mild to moderate group. There was significant difference between the two groups (P <0.05). Conclusions It is thought that the decrease of serum vitamin B12 level is the main reason of lacunar infarction. Controlling the diet of patients and getting enough vitamin B12 can effectively prevent the occurrence of lacunar infarction and improve the quality of life .