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目的探讨复方丹参在过敏性紫癜患儿的治疗作用。方法 2004-01-2010-01收治的过敏性紫癜儿童118例进行随机分组,其中治疗组60例,对照组58例。对照组给予氯苯那敏0.1mg/(kg·次),3次/d,葡萄糖酸钙0.5ml/(次·d),最大量20ml。腹痛者加用山菪莨碱,消化道出血者加用西米替丁。治疗组在对照方案的基础上加用复方丹参针剂静脉滴注,两组疗程均为7～10d。结果治疗组显效39例,有效16例,无效5例,总有效率91.7%,对照组显效21例,有效25例,无效14例,有效率76.7%。治疗组优于对照组(P<0.05)。结论复方丹参治疗小儿过敏性紫癜有明显疗效,无明显不良反应,值得临床应用推广。
Objective To investigate the therapeutic effect of compound Salvia miltiorrhiza on children with Henoch-Schonlein purpura. Methods A total of 118 children with allergic purpura admitted from January 2004 to June 2010 were randomly divided into treatment group (60 cases) and control group (58 cases). The control group was given chlorpheniramine 0.1mg / (kg · times), 3 times / d, calcium gluconate 0.5ml / (times · d), the maximum amount of 20ml. Abdominal pain plus mountain scopolamine plus gastrointestinal bleeding plus cimetidine. The treatment group in the control program based on the use of compound Salvia injection intravenous drip, the two courses were 7 ~ 10d. Results In the treatment group, 39 cases were markedly effective, 16 cases were effective, 5 cases were ineffective and the total effective rate was 91.7%. In the control group, 21 cases were markedly effective, 25 cases were effective and 14 cases were ineffective with an effective rate of 76.7%. The treatment group was better than the control group (P <0.05). Conclusion Compound Salvia treatment of children with Henoch-Schonlein purpura have significant effect, no significant adverse reactions, it is worth promoting the clinical application.