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乳腺癌是女性常见的恶性肿瘤之一 ,其死亡率与癌细胞的浸润、转移有密切关系。组织中基质金属蛋白酶 (ＭＭＰｓ)与金属蛋白酶组织抑制因子(ＴＩＭＰｓ)间的活性的平衡调节破坏是导致肿瘤细胞侵袭和转移的重要原因[1] 。我们应用免疫组化Ｓ Ｐ法 ,检测上述ＭＭＰｓ在 5 8例乳腺?
Breast cancer is one of the most common malignant tumors in women. The mortality rate is closely related to the infiltration and metastasis of cancer cells. Tissue destruction of the balance between matrix metalloproteinases (MMPs) and metalloproteinase tissue inhibitors (TIMPs) is a major cause of tumor cell invasion and metastasis [1]. We applied immunohistochemical SP method to detect the above MMPs in 58 cases of breast?