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恶性肿瘤细胞的侵袭和转移是肿瘤患者死亡的主要原因,而淋巴道和血道转移是肿瘤远处转移的主要途径,故肿瘤淋巴管形成的研究是肿瘤学研究的热点。随着血管内皮生长因子-C(vascu lar endothelial growth factor-C,VEGF-C)[1]和血管内皮生长因子-D(vascu lar endothelial growth
The invasion and metastasis of malignant tumor cells are the main cause of death of tumor patients. Lymphatic and hematogenous metastasis are the main pathways of distant metastasis. Therefore, the study of lymphangiogenesis is a hot topic in oncology research. With the development of vascu lar endothelial growth factor-C (VEGF-C) [1] and vascu lar endothelial growth