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自从抗逆转录病毒治疗问世以后,获得性免疫缺陷综合征患者的寿命延长。获得性免疫缺陷综合征患者冠心病和心肌梗死的危险性高于一般人群。其病因与这些患者冠心病危险因素增加、人类免疫缺陷病毒感染本身及抗逆转录病毒治疗等有关。慢性炎症和免疫激活也在冠心病的病理生理中发挥重要作用。
Life expectancy has increased in patients with acquired immunodeficiency syndrome since the advent of antiretroviral therapy. Patients with acquired immune deficiency syndrome have a higher risk of coronary heart disease and myocardial infarction than the general population. The etiology of these patients with coronary heart disease risk factors increased, human immunodeficiency virus infection itself and antiretroviral therapy and so on. Chronic inflammation and immune activation also play an important role in the pathophysiology of coronary heart disease.