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本文作者在152例多发性骨髓瘤(MM)患者中验证了文献中7种 MM 的临床分期方法的预后价值。患者中位年龄为85岁(范围36—89岁),男性95例,女性57例。1、急性白血病 B 组(ALGB)和东部地区肿瘤协作组(ECOG,1973)的分期方法:将符合下列标准之一的患者确定为“高危组”:①血尿素>10mmol/1,②血清钙>3 mmol/1,③确诊时有严重感染,④白细胞数在4×10~9/1以下,血小板数在100×10~9/l 以下,⑤预计存活时间不超过2个月。
The authors validated the prognostic value of clinical staging of seven MM in the literature in 152 patients with multiple myeloma (MM). The median age was 85 years (range, 36-89 years), 95 males and 57 females. 1. Phases of acute leukemia group B (ALGB) and Eastern Cooperative Oncology Group (ECOG, 1973): Patients with one of the following criteria were identified as “high risk group”: ① blood urea> 10 mmol / 1, ② serum calcium > 3 mmol / l, ③ Serious infection at diagnosis, ④ The number of white blood cells is below 4 × 10 ~ 9/1 and the number of platelets is below 100 × 10 ~ 9 / l. ⑤ Expected survival time is less than 2 months.