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目的了解乳母服用200 mg碘油胶丸前后乳汁碘的动态变化。方法在新疆阿克苏地区库车县牙哈镇的4个村选择109名近半年内未服用过碘油丸的19～36岁哺乳期妇女,采用现场干预的方法,并于服药前、服药后的第1、3、7、14、30、50、75、100 d分别采集服药组及对照组乳汁,进行碘含量测定。结果阿克苏地区库车县牙哈镇的四村乳母109人(服药组59人、对照组50人),服药前乳汁碘中位数为89.5μg/L,口服200 mg碘油胶丸后,乳汁碘中位数于第一天达到高峰,为1 004.1μg/L,服药后100 d乳汁碘中位数为152.3μg/L,补碘干预可提高乳碘水平。结论口服200 mg碘油胶丸可达到较好的干预效果。
Objective To understand the dynamic changes of milk iodine before and after taking 200 mg lipiodol capsules. Methods A total of 109 lactating women aged 19-36 years who had not taken iodized oil in the past six months were enrolled in 4 villages in Yaha Town, Kuqa County, Xinjiang Uygur Autonomous Region. On the 1st, 3rd, 7th, 14th, 30th, 50th, 75th and 100th days, the milk of the medication group and the control group were collected to determine the content of iodine. Results A total of 109 maternal lactating women (59 in control group and 50 in control group) in Yaha Town, Kuqa County, Aksu Prefecture were enrolled in this study. The median iodine in milk before treatment was 89.5 μg / L. After oral administration of 200 mg lipiodol capsules, The median iodine peaked at 1 004.1 μg / L on the first day, and the median iodine in milk at 100 days after oral administration was 152.3 μg / L. The iodine supplementation increased the level of milk iodine. Conclusion Oral administration of 200 mg lipiodol capsule can achieve better intervention effect.