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目的 分析子宫颈解脲支原体 (UU)和沙眼衣原体 (CT)感染情况 ,观察大环内脂类、四环素类联合干扰素的治疗效果。方法 应用荧光定量PCR方法 ,对宫颈炎、白带异常的 3974例女性患者取宫颈拭子进行UU、CT病原体检测。结果 检出病原体 732例 ,检出率为 18 4 2 %。其中UU 5 0 8例 (12 78% ) ,CT176例 (4 4 3% ) ,混合感染 4 8例 (1 2 1% )。阿奇霉素、米诺环素联合干扰素治疗总转阴率 92 85 %。结论 UU、CT是子宫颈性传播疾病感染的主要病原体 ,其感染率UU >CT ,联合用药效果满意
Objective To analyze the infection of UU and CT, and to observe the therapeutic effect of macrolide and tetracycline combined with interferon. Methods Fluorescent quantitative PCR was used to detect the pathogen of UU and CT in 3974 female patients with cervicitis and leucorrhea. Results 732 pathogens were detected, the detection rate was 18 4 2%. Among them, 588 (12 78%) were UU, 176 (74.3%) were CT, and 48 were mixed infection (121%). Azithromycin, minocycline combined with interferon treatment of total negative rate of 92 85%. Conclusions UU and CT are the main pathogens of infection of cervix sexually transmitted diseases. The infection rate is UU> CT, and the effect of combination therapy is satisfactory