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用人类胎肝低分子天然抑瘤物(LMW-NTS)对13例缓解期(CR)急性白血病体外净化后自体骨髓移植(ABMT)。其中ALL4例(CR_13例,CR_21例),ANLL9例(CR_17例,CR_22例)。12例获造血重建,1例死于霉菌败血症。移植后持续缓解8例,缓解时间>12个月7例,>6个月1例。4例移植后3～6个月复发。本文对该净化方法及ABMT近期疗效进行讨论。
In vitro purified bone marrow transplantation (ABMT) was performed on 13 CR patients with LMW-NTS. ALL4 cases (CR_13 cases, CR_21 cases), ANLL9 cases (CR_17 cases, CR_22 cases). 12 cases of hematopoietic reconstructions, 1 case died of mold septicemia. Eight patients sustained remission after transplantation, remission time> 12 months in 7 cases,> 6 months in 1 case. 4 cases relapsed 3 to 6 months after transplantation. This article discusses the decontamination method and the recent efficacy of ABMT.