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对120例经手术、病理证实为原发性醛固酮增多症(PA)患者的临床资料进行回顾性分析。结果显示:皮质腺瘤 98例(81.7%),皮质增生22例(18.3%)。手术前血清钾降低者 114例(95.0%),最低者达 1.6 mmol/L。测定103例血浆醛固酮均高于正常,测定91例血浆肾素活性54例低于正常(59.3%)。B超检查106例,阳性72例(67.9%),CT检查110例,阳性105例(95.5%)。手术后120例血清钾均恢复正常。说明PA的定性诊断主要依赖患者的血清钾降低及血浆醛固酮升高,B超及CT定位诊断较为准确。治疗方法以开放性手术切除肿瘤侧肾上腺为主。
The clinical data of 120 patients with pathologically confirmed primary aldosteronism (PA) were analyzed retrospectively. The results showed that: 98 cases of cortical adenoma (81.7%), 22 cases of cortical hyperplasia (18.3%). Preoperative serum potassium decreased in 114 cases (95.0%), the lowest was 1.6 mmol / L. Determination of 103 cases of plasma aldosterone were higher than normal, measured 91 cases of plasma renin activity 54 cases were lower than normal (59.3%). B ultrasound examination in 106 cases, positive in 72 cases (67.9%), CT examination in 110 cases, positive in 105 cases (95.5%). 120 cases of serum potassium returned to normal after surgery. Description of the qualitative diagnosis of PA mainly depends on the patient’s serum potassium and plasma aldosterone increased, B ultrasound and CT location diagnosis is more accurate. Treatment of open surgical excision of the tumor side of the adrenal based.