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目的:分析非典型子宫内膜增生应用醋酸甲羟孕酮治疗的临床效果及症状改善情况。方法:选取濮阳市妇幼保健院2015年6月至2017年1月收治的非典型子宫内膜增生患者共90例,按照随机数字表法将其分成参照组和研究组,每组45例。将戊酸雌二醇片和醋酸甲羟孕酮分别应用于两组患者临床治疗,对比相关临床指标数据变化情况。结果:相比于参照组,研究组患者临床治疗总有效率更高,差异具有统计学意义(P<0.05),患者的月经失血图评分和子宫内膜厚度指标数据均更低,差异具有统计学意义(P<0.05),该组患者临床疗效显著,症状改善更明显。结论:非典型子宫内膜增生患者在临床治疗中应用醋酸甲羟孕酮临床效果更好,用药后能够在第一时间控制病情发展,改善患者临床症状。
Objective: To analyze the clinical effect and symptom improvement of atypical endometrial hyperplasia treated with medroxyprogesterone acetate. Methods: A total of 90 patients with atypical endometrial hyperplasia who were treated in Puyang Maternal and Child Health Hospital from June 2015 to January 2017 were selected and divided into the reference group and the study group according to the random number table method, with 45 cases in each group. The estradiol valerate tablets and medroxyprogesterone acetate were applied to the clinical treatment of two groups of patients, comparing the changes of clinical data. Results: Compared with the reference group, the total effective rate of clinical treatment in study group was higher, the difference was statistically significant (P <0.05), and the index of menstrual blood loss and endometrial thickness were lower, the difference was statistically significant Significance (P <0.05), the clinical efficacy of this group was significantly improved more obvious symptoms. Conclusion: The clinical application of medroxyprogesterone acetate in clinical treatment of patients with atypical endometrial hyperplasia is better. After treatment, the disease can be controlled for the first time and the clinical symptoms are improved.