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目的探讨注射用炎琥宁与利巴韦林治疗上呼吸道感染患儿的临床效果。方法选取2013年1月至2014年1月广东省深圳市边防支队卫生队收治的174例上呼吸道感染患儿为研究对象,按随机数字表法将其分为炎琥宁组和利巴韦林组,各87例。两组患儿在确诊后均立即接受常规对症治疗,同时炎琥宁组患儿给予注射用炎琥宁,利巴韦林组患儿采用利巴韦林,比较两组患儿治疗效果、不良反应及复发情况。结果治疗后,炎琥宁组患儿体温为(37.1±1.0)℃,明显低于利巴韦林组的(38.1±1.1)℃,差异有统计学意义(t=3.397,P<0.05);炎琥宁组患儿退热、咳嗽缓解、鼻塞流涕停止及咽部充血消失时间均明显短于利巴韦林组,差异均有统计学意义(均P<0.05);炎琥宁组患儿的总有效率明显高于利巴韦林组,差异有统计学意义(P<0.05);炎琥宁组患儿不良反应发生率及病情复发率均明显低于利巴韦林组,差异均有统计学意义(均P<0.05)。结论注射用炎琥宁与利巴韦林均可有效改善上呼吸道感染患儿的临床症状,但注射用炎琥宁的临床疗效和安全性更佳,在缩短病程、促进康复、防止复发等方面优势更明显。
Objective To investigate the clinical effects of injection of Yanhu Ning and Ribavirin in the treatment of children with upper respiratory tract infection. Methods From January 2013 to January 2014, Shenzhen border defense detachment health team admitted to the 174 cases of upper respiratory tract infection in children as the research object, according to random number table method is divided into Yanhuning group and ribavirin Group, each 87 cases. The two groups of children were diagnosed immediately after conventional symptomatic treatment, while the Yan-Huning group given injection of Yan Hu-Ning, ribavirin group with ribavirin, the two groups were compared with the treatment effect, poor Response and recurrence. Results After treatment, the body temperature of Yanhuning group was significantly lower than that of ribavirin group (37.1 ± 1.0 ℃) (38.1 ± 1.1 ℃), the difference was statistically significant (t = 3.397, P <0.05). Yanhuning group of patients with fever, relieve cough, nasal obstruction runny nose and throat congestion and disappearance of time were significantly shorter than the ribavirin group, the difference was statistically significant (P <0.05) The total effective rate of children was significantly higher than that of ribavirin group, the difference was statistically significant (P <0.05); the incidence of adverse reactions and relapse rate in children with Yanhuning were significantly lower than the ribavirin group, the difference All were statistically significant (P <0.05). Conclusion Injection of both Yan Hu Ning and ribavirin can effectively improve the clinical symptoms of children with upper respiratory tract infection, but the clinical efficacy and safety of injection of Yan Hu Ning better, shorten the course, promote rehabilitation, prevent recurrence and so on The advantage is more obvious.