早发型重度子痫前期发病对妊娠结局的影响

• 作 者: 侯美芹
• 机 构: 上海市第八人民医院,
• 出 处: 中国妇幼保健
• 发表日期: 2011年32期
• 关键词: 早发型重度子痫前期 时间因素 期待治疗 妊娠结局

目的:分析早发型重度子痫前期(EOSP)发病时间对妊娠结局的影响,探讨期待保守治疗EOSP的临床意义。方法:将71例EOSP按发病时孕周分为A组(孕28～31+6周)28例和B组(孕32～34周)43例,比较两组发病孕周、终止妊娠孕周、孕周延长时间、严重并发症发生情况、胎儿及新生儿病死率。结果:围生儿病死率A组为21.4%,B组为11.4%;孕产妇并发症发生率A组为65.6%,B组为为51.3%;组间比较差异有统计学意义(P<0.05)。结论:早发型重度子痫前期发病孕周越早,新生儿死亡率越高;短期的保守治疗可有效延长孕周,改善围生儿预后。

Objective: To analyze the influence of onset time of early onset severe preeclampsia (EOSP) on pregnancy outcome and explore the clinical significance of expectant conservative treatment of EOSP. Methods: Seventy-one EOSPs were divided into group A (28-31 ± 6 weeks), group B (43 cases) and group B (43-34 weeks). According to the gestational age, 71 cases were divided into two groups: gestational age , Prolonged gestational age, the incidence of serious complications, fetal and neonatal mortality. Results: Perinatal mortality was 21.4% in group A and 11.4% in group B, respectively. The incidence of maternal complications in group A was 65.6% in group A and 51.3% in group B. The difference between groups was statistically significant (P <0.05 ). Conclusions: The earlier the gestational age of early-onset severe preeclampsia is, the higher the neonatal mortality rate is. The short-term conservative treatment can effectively prolong the gestational age and improve the prognosis of perinatal infants.