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目的:探讨脑缺血再灌损伤中补体的作用.方法:以大鼠局灶脑缺血再灌为动物模型,运用免疫组化方法检测缺血2H,再灌22H的脑梗塞组织中补体C3的沉积及降纤酶干预结果.结果:补体在脑缺血再灌组织中大量沉积,给予降纤酶后补体沉积减少,补体沉积与组织坏死之间有密切关系(P＜0.01).结论:脑缺血再灌损伤中有补体参与,补体参与与组织坏死有密切关系,补体沉积减少后,脑组织损伤相应减轻“,”Objective: To demonstrate complement (C3) deposition in reperfusions tissues and to study complements function in cerebral ischemia reperfusion injury. Methods: Rat models of 2 hour middle cerebral artery occlusion with 22 hour reperfusion were used and defibrase was administered 1.5 hours after occlusion in one of the groups, then by immunohistochemical method we detected C3 deposition in each group. Results: C3 deposition was remarkable in ischemia reperfusion tissues, and the deposition was weak in ...