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本文报道对地方性克汀病患者进行了临床神经病学检查,包括传统的椎体神经系统检查,而且注意检查了椎体外系统,特别对智力功能做了比较精细的研究。同时观察了垂体甲状腺功能,结果表明克汀病组血清T_4值较正常对照组低而TSH值高(P<0.05)。血清hGH空腹值两组无差别,但用左旋多巴兴奋后60分钟及90分钟值克汀病组低于正常对照组(P<0.05)。运用左旋多巴刺激试验证实地方性克汀病人垂体人类生长激素储备功能差,是一个新发现,有利于对碘缺乏病史深入地研究。
This article reports the clinical neurological examination of patients with endemic cretinism, including the traditional vertebral nervous system examination, and examines the extrapyramidal system, in particular, made a more detailed study of mental function. The pituitary thyroid function was observed at the same time. The results showed that serum T 4 value in cretinism group was lower than that in normal control group and TSH value was higher (P <0.05). Serum hGH fasting value of the two groups no difference, but 60 minutes after levodopa and 90 minutes cretinism group was lower than the normal control group (P <0.05). The use of levodopa stimulation test confirmed that endemic cretinism in human pituitary ghrelin poor reserve function is a new discovery, is conducive to the history of iodine deficiency in-depth study.