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目前认为,内脏脂肪组织堆积是冠状动脉粥样硬化性心脏病重要的危险因素。心外膜脂肪组织是内脏脂肪的一种类型,除了发挥代谢、产热和机械作用,还能分泌多种脂肪因子直接作用于邻近的冠状动脉,进而影响冠状动脉粥样硬化性心脏病进程。本文从解剖学、生理学、病理学、病理生理学和循证医学角度对心外膜脂肪组织与冠状动脉粥样硬化性心脏病关系及其机制的研究进展做一综述。
It is currently believed that visceral adipose tissue accumulation is an important risk factor for coronary atherosclerotic heart disease. Epicardial adipose tissue is a type of visceral fat, in addition to exert metabolism, heat and mechanical effects, but also the secretion of a variety of adipokines directly affect the adjacent coronary artery, and thus affect the process of coronary heart disease. This article reviews the research progress of the relationship between epicardial adipose tissue and coronary atherosclerotic heart disease in anatomy, physiology, pathology, pathophysiology and evidence-based medicine.