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观察喉癌根治术中异氟醚麻醉切喉时期应用异丙酚减轻循环副反应。４０例喉癌根治术异氟醚麻醉患者，随机分为切喉时应用异丙酚（Ａ组）和不用异丙酚（Ｂ组）两组。Ａ组病人切喉后５～１５ｍｉｎ，血压、心率明显低于Ｂ组（Ｐ＜００５）。切喉后５～４５ｍｉｎ，Ａ组血压、心率均在正常水平；Ｂ组切喉后５、１５、３０ｍｉｎ与切喉前相比较血压均有明显上升（Ｐ＜００５）；切喉后５、１５ｍｉｎ心率明显增快（Ｐ＜００５）。结果表明，异氟醚麻醉复合小剂量异丙酚在切喉时可减轻切喉所致的心血管副反应，使患者的循环功能更为平稳。
To observe the application of propofol during isoflurane anesthesia in laryngeal radical mastectomy to reduce the side effects of circulation. Forty patients with laryngeal carcinoma undergoing isoflurane anesthesia were randomly divided into two groups: propofol (group A) and no propofol (group B). A group of patients 5 ~ 15min after laryngectomy, blood pressure, heart rate was significantly lower than the B group (P <0 05). The blood pressure and heart rate of group A were all normal at 5 ~ 45min after laryngectomy. Blood pressure was significantly increased at 5, 15 and 30 minutes after laryngectomy in group B (P <005) , 15min heart rate was significantly faster (P <0 05). The results showed that isoflurane anesthesia combined with low-dose propofol in the throat can reduce the cutaneous throat due to cardiovascular side effects, so that patients with more stable circulation.