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作者将5只成年猫模拟暴露到海拔5 500m高度,3～4周后,测定了等二氧化碳低氧通气反应(HVR)和颈动脉窦神经(CSN)等二氧化碳低氧反应。结果:暴露3～4周后,HVR明显降低。HVR斜率参数A值,未麻醉猫由暴露前的53.9±10.1降到14.8±1.8(p<0.05),麻醉猫由50.2±8.2降到8.5±1.8(p<0.05)。未麻醉猫呼吸低氧空气时,P_(ET) CO_2由4.44±0.16降到3.74±0.17kPa。为了除外低二氧化碳对HVR所起的那一部分影响,作者测
The authors simulated exposure of 5 adult cats to an altitude of 5 500 m. After 3 to 4 weeks, carbon dioxide hypoxia responses such as carbon dioxide hypoxic ventilation (HVR) and carotid sinus nerve (CSN) were measured. Results: After 3 to 4 weeks of exposure, HVR was significantly reduced. The value of HVR slope parameter A decreased from 53.9 ± 10.1 before exposure to 14.8 ± 1.8 (p <0.05) and from 50.2 ± 8.2 to 8.5 ± 1.8 (p <0.05) in anesthetized cats. The P_ (ET) CO_2 decreased from 4.44 ± 0.16 to 3.74 ± 0.17 kPa when the non-anesthetized cats inhaled hypoxic air. To exclude that part of the effect of low carbon dioxide on HVR, the authors measured