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目的 探讨血细胞形态学观察对苯作业工人健康监护和早期预防苯中毒的意义。方法 常规采苯作业工人末梢或静脉血进行WBC、RBC和PLT计数 ,测定HGB浓度 ,并对WBC、RBC、PLT作形态学观察。结果 在 12 0名苯作业工人中共检出 35名异常工人 ,其中有 18名全血细胞减少 ;血细胞的形态学改变以中性粒细胞胞浆出现中毒颗粒和空泡最常见。结论 中性粒细胞出现中毒颗粒和空泡是接触苯后血液系统的早期改变 ,随后是白细胞减少和全血细胞减少。血细胞形态学指标可作为苯作业工人健康监护和早期预防苯中毒的重要指标
Objective To investigate the significance of blood cell morphological observation on the health monitoring of benzene workers and the early prevention of benzene poisoning. Methods WBC, RBC and PLT were counted in peripheral blood or peripheral venous blood collected from workers exposed to benzene. The concentrations of HGB were measured and the morphological changes of WBC, RBC and PLT were observed. Results A total of 35 abnormal workers were detected in 120 workers exposed to benzene, including 18 cases of pancytopenia. The morphological changes of blood cells were most common in neutrophil cytoplasm with toxic particles and vacuoles. Conclusion Neutrophil poisoning granules and vacuoles are early changes in the blood system after exposure to benzene, followed by leukopenia and pancytopenia. Blood cell morphological indicators can be used as workers benzene health monitoring and early detection of benzene poisoning an important indicator