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目的探讨两种抗生素治疗小儿肺炎的成本-临床疗效比较。方法将我院诊治的100例小儿肺炎患者随机将其分为头孢唑林组和头孢呋辛组,每组各50例,对两组疗效进行评价。结果 50例头孢唑林组患者中,47例治愈,2例显效,1例好转,0例无效;50例头孢呋辛组患者中,45例治愈,1例显效,2例好转,2例无效。与头孢呋辛组的治愈率(96.00%)相比,头孢唑林组的治愈率相对较高(100.00%),但差异无统计学意义(P>0.05)。在用药过程中,两组患儿都没有出现与药物治疗有关的严重不良反应。与头孢唑林组药物成本(1035.50元)相比,头孢呋辛组的药物成本明显降低(915.50元),P<0.05。结论相对于头孢呋辛钠而言,头孢唑林钠治疗小儿肺炎更加经济实惠,值得临床推广。
Objective To investigate the cost-effectiveness of two antibiotics in children with pneumonia. Methods 100 pediatric pneumonia patients diagnosed and treated in our hospital were randomly divided into cefazolin group and cefuroxime group, with 50 cases in each group. The curative effect was evaluated. Results Among the 50 cases of cefazolin group, 47 cases were cured, 2 cases were markedly effective, 1 case improved and 0 case ineffective. Among the 50 cases of cefuroxime group, 45 cases were cured, 1 case markedly improved, 2 cases improved and 2 cases ineffective . Compared with the cure rate of cefuroxime group (96.00%), the cure rate of cefazolin group was relatively high (100.00%), but the difference was not statistically significant (P> 0.05). In the course of medication, no serious adverse reactions related to drug treatment occurred in both groups of children. Compared with the cost of cefazolin group drug (1035.50 yuan), the drug cost of cefuroxime group was significantly lower (915.50 yuan), P <0.05. Conclusion Compared to cefuroxime sodium, cefazolin sodium treatment of children with pneumonia is more affordable, worthy of clinical promotion.