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急性一氧化碳中毒(ACMP)在我国是中毒的重要病因之一,急性一氧化碳中毒后迟发性脑病(DEACMP)是急性一氧化碳中毒后最严重的并发症之一,目前发病机制尚未明确。通过对DEACMP患者行磁共振波谱研究显示患者病变大脑各代谢物比值相对浓度及比值发生有统计学意义的改变;通过对DEACMP患者行磁共振弥散张量成像研究显示患者白质纤维破坏。现主要对磁共振波谱及磁共振弥散张量成像在DEACMP的研究应用现状予以综述。
Acute carbon monoxide poisoning (ACMP) is one of the important causes of poisoning in our country. Delayed encephalopathy (DEACMP) after acute carbon monoxide poisoning is one of the most serious complication after acute carbon monoxide poisoning. The pathogenesis is not yet clear. By DEACMP patients with magnetic resonance spectroscopy showed that patients with lesions of the brain metabolite ratio relative concentration and the ratio of a statistically significant change; through the DEACMP patients with magnetic resonance diffusion tensor imaging study showed that patients with white matter fiber damage. Now mainly the magnetic resonance spectroscopy and magnetic resonance diffusion tensor imaging in the research and application of DEACMP are reviewed.