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目的了解四川省大骨节病病情现状,指导重点病区的预防控制工作,为评估控制和消除大骨节病提供科学依据。方法各病区县以村为单位,对调查点内7～12岁儿童进行大骨节病临床检查和右手正位X线拍片。结果 2005-2009年共调查7～12岁儿童13472人,临床检出阳性72人,平均临床检出率0.53%(0～1.07%);X线检出阳性373人,平均X线检出率2.77%(1.55%～4.86%),干骺端阳性率为2.06%(0.47%～3.68%),骨端阳性率为0.70%(0.28%～4.39%),骨骺阳性率为0.05%(0～0.09%),腕骨阳性率为0.01%(0～0.09%),仅有1例三联征。X线检出率大于10%的病区村所占比例呈下降趋势,活跃病区村主要集中在阿坝州地区。结论四川省大骨节病病情稳定,儿童新发得到有效控制,仅个别地区病情仍然较重。提示今后应该加强重点地区监测,在病情活跃地区采取有针对性的防治措施。
Objective To understand the current situation of Kashin-Beck disease in Sichuan Province and to guide the prevention and control of key wards in order to provide a scientific basis for evaluating control and eliminating Kashin-Beck disease. Methods The ward counties in the village as a unit, the investigation point within 7 to 12-year-old children for Kashin-Beck disease clinical examination and right hand X-ray film. Results A total of 13,472 children aged 7-12 years were surveyed from 2005 to 2009, 72 were positive, the average clinical detection rate was 0.53% (0 ~ 1.07%). The positive rate of X-ray examination was 373 and the average X-ray detection rate The positive rate of metaphysis was 2.06% (0.47% -3.68%), while the positive rate of metaphysis was 0.70% (0.28% ~ 4.39%). The positive rate of epiphysis was 0.05% (0 ~ 0.09%), the positive rate of carpal bone was 0.01% (0 ~ 0.09%), only one case of triad. X-ray detection rate of more than 10% of the ward has shown a downward trend in the proportion of villages, active ward village mainly in Aba Prefecture. Conclusions Kashin-Beck disease is stable in Sichuan province and new onset of children is effectively controlled. In some areas, the condition is still severe. Prompted in the future should strengthen the monitoring of key areas, active areas in the disease to take targeted control measures.