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目的探讨内镜下美蓝染色联合超声内镜检查对早期胃癌的诊断价值。方法 80例可疑胃病变者在内镜下美蓝染色,在着色深、表面不平整或染色不规则区域多点活检,对病理结果为高级别上皮内瘤变和癌变者再进行超声内镜检查。结果美蓝染色有67例着色深(83.8%,67/80)。其中癌变8例(11.9%,8/67)、上皮内瘤变18例(低级别14例、高级别4例)(26.9%,18/67)、炎症41例(61.2%,41/67)。超声内镜检查发现早期癌8例,其中3例为黏膜层癌,5例为黏膜下层癌。高级别上皮内瘤变者病变局限于上皮层和黏膜层。结论内镜下美蓝染色联合超声内镜检查能减少胃黏膜活检误诊,提高早期胃癌诊断率,值得临床推广应用。
Objective To investigate the diagnostic value of endoscopic mebano staining combined with endoscopic ultrasonography in early gastric cancer. Methods Eighty patients with suspected gastric lesions underwent methylene blue endoscopy and performed multiple biopsies with deep staining, irregular surface, or irregular staining. Endoscopic ultrasonography was performed for high-grade intraepithelial neoplasia and carcinogenesis. . Results Methylene blue stained 67 cases with deep staining (83.8%, 67/80). There were 8 cases of cancer (11.9%, 8/67), 18 cases of intraepithelial neoplasia (14 cases of low grade, 4 cases of high grade) (26.9%, 18/67), and 41 cases of inflammation (61.2%, 41/67). . Endoscopic ultrasonography revealed early cancer in 8 cases, including 3 cases of mucosal carcinoma and 5 cases of submucosal carcinoma. High grade intraepithelial neoplasia lesions are confined to the epithelial and mucosal layers. Conclusion Methylene blue staining combined with endoscopic ultrasonography can reduce the misdiagnosis of gastric mucosal biopsy and improve the diagnostic rate of early gastric cancer. It is worthy of clinical application.