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目的:探讨清热益气法联合西药治疗冠心病心绞痛患者的疗效以及对不良事件的预防效果。方法:选取2015年2月—2016年3月在我院接受治疗的冠心病心绞痛患者100例,采用随机数表法将所有的入选患者分为观察组和对照组两组,每组各50例,对照组患者给予西药治疗,观察组患者给予清热益气法联合西药治疗,比较两组患者治疗后血液流变学变化、血脂变化、临床疗效以及不良反应发生率情况。结果:治疗后,两组患者的血浆黏度、全血黏度以及纤维蛋白都有所下降,观察组(1.02±0.12)mpa·s、(2.13±0.56)mpa·s、(2.12±0.56)g/L低于对照组(2.12±0.30)mpa·s、(3.78±0.19)mpa·s、(3.02±0.26)g/L,两组比较差异显著(P<0.05);治疗后,两组患者的TG以及TC都有所下降,观察组(0.98±0.12)、(3.12±0.78)mmol/L低于对照组(1.56±0.13)、(4.98±0.99)mmol/L,两组比较差异显著(P<0.05);两组患者的HDL-C都有所升高,观察组(1.98±0.20)mmol/L高于对照组(1.10±0.09)mmol/L,两组比较差异显著(P<0.05);观察组患者治疗后的总有效率为96.00%高于对照组78.00%,两组比较差异显著(P<0.05)。两组患者治疗后不良反应发生率比较无统计学意义(P>0.05)。结论:清热益气法联合西药治疗冠心病心绞痛患者,可有效提高临床治疗效果且不良反应发生率低。
Objective: To investigate the efficacy of Qingre Yiqi method combined with Western medicine in the treatment of patients with angina pectoris of coronary heart disease and its preventive effect on adverse events. Methods: 100 patients with coronary heart disease and angina pectoris who were treated in our hospital from February 2015 to March 2016 were selected. All the patients were divided into observation group and control group by random number table method, 50 cases in each group The patients in the control group were given Western medicine. The patients in the observation group were treated with Qingre Yiqi method combined with western medicine. The changes of blood rheology, blood lipid, clinical efficacy and the incidence of adverse reactions were compared between the two groups. Results After treatment, the plasma viscosity, whole blood viscosity and fibrin of the two groups decreased. The levels of (1.02 ± 0.12) mpa · s, (2.13 ± 0.56) mpa · s and (2.12 ± 0.56) g / L was significantly lower than that of the control group (2.12 ± 0.30) mpa · s, (3.78 ± 0.19) mpa · s and (3.02 ± 0.26) g / L, respectively TG and TC decreased in the observation group (0.98 ± 0.12) and (3.12 ± 0.78) mmol / L compared with the control group (1.56 ± 0.13) and (4.98 ± 0.99) mmol / L, respectively (P <0.05). The HDL-C levels in both groups were significantly higher than those in the control group (1.98 ± 0.20 mmol / L vs 1.10 ± 0.09 mmol / L, . The total effective rate of observation group after treatment was 96.00%, which was significantly higher than that of control group (78.00%). There was significant difference between the two groups (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups after treatment (P> 0.05). Conclusion: Qingre Yiqi method combined with Western medicine in patients with coronary heart disease angina pectoris can effectively improve the clinical effect and the incidence of adverse reactions is low.