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目的了解小剂量红霉素对早产儿喂养不耐受的防治效果。方法选择2005年1月～2007年1月期间于我院生产的早产儿140例为研究对象,随机分为干预组和对照组。两组均予以常规治疗,干预组在常规治疗基础上予以小剂量红霉素。结果(1)干预组喂养不耐受发生率为20.83%(15/72),对照组发生率为73.53%(50/68)。两组喂养不耐受发生率经X2检验,p<0.05。(2)对照组发生的50例喂养不耐受患儿予以小剂量红霉素治疗,治疗总有效率为76.00%。结论采用小剂量红霉素对预防和治疗早产儿喂养不耐受均具有积极的作用。
Objective To understand the preventive and therapeutic effects of low dose erythromycin on intolerance of premature infants. Methods 140 cases of preterm infants born in our hospital from January 2005 to January 2007 were selected as research object and randomly divided into intervention group and control group. Both groups were routinely treated, and the intervention group was given low dose erythromycin on the basis of routine treatment. Results (1) The incidence of feeding intolerance in intervention group was 20.83% (15/72), while that in control group was 73.53% (50/68). The incidence of feeding intolerance in both groups was tested by X2, p <0.05. (2) The control group occurred in 50 cases of intolerant children with low-dose erythromycin treatment, the total effective rate was 76.00%. Conclusion The use of low-dose erythromycin has a positive effect on the prevention and treatment of intolerance in preterm infants.