论文部分内容阅读
目的 评价奥曲肽治疗上消化道大出血的临床效果。方法 使用奥曲肽治疗上消化道大出血 139例 ,与垂体后叶素治疗食管胃底静脉曲张破裂大出血 (EGVB) 4 6例和洛赛克治疗胃十二指肠溃疡出血 41例的疗效进行对比。结果 奥曲肽治疗上消化道大出血总有效率为 89 2 1% ,其中治疗食管胃底静脉曲张性大出血有效率为81 82 % ,明显高于垂体后叶素组 (6 0 87% ,P <0 0 5 ) ;治疗胃十二指肠道溃疡引起的大出血有效率为 91 0 3% ,与洛赛克组 (96 10 % )比较差异无显著意义 (P >0 0 5 ) ;治疗其他原因引起的出血有效率为 10 0 0 0 %。结论 奥曲肽对各种原因引起的上消化道大出血均有较好疗效 ,可作为治疗上消化道大出血的首选药物。
Objective To evaluate the clinical effect of octreotide in treating upper gastrointestinal bleeding. Methods 139 patients with upper gastrointestinal bleeding were treated with octreotide, and compared with 46 patients with posterior pituitary esophageal variceal bleeding (EGVB) and 41 patients with gastrointestinal ulcer hemorrhage treated with Losec. Results The total effective rate of octreotide in the treatment of upper gastrointestinal bleeding was 89 2 1%. The effective rate of treatment for esophageal variceal bleeding was 81 82%, which was significantly higher than that of pituitrin group (60 87%, P 0 0 5). The effective rate of treating hemorrhage caused by gastroduodenal ulcer was 91 0 3%, which was not significantly different from that of Losec group (96 10%) (P 0 05). The treatment of other causes The effective rate of bleeding was 100%. Conclusion Octreotide has good curative effect on upper gastrointestinal hemorrhage caused by various causes and can be used as the first choice of drug for the treatment of upper gastrointestinal bleeding.