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人们已认识到,具有质和量的免疫缺陷病的病种很多,但具有特异性体液抗体缺陷而伴有正常量IgG,IgA,IgM及IgE的病人,过去仅报告2例。本文介绍1例反复呼吸道感染提示为免疫缺陷病的病人。其细胞免疫及体液免疫成分及淋巴结的组织学所见均正常,但在抗原攻击之后有特异性体液免疫的选择性缺陷。病例:患儿足月顺产,母亲妊娠期正常,没有对感染异常敏感的家族史。13个月时因反复鼻寒流涕入院。入院时血清IgG为870mg%,IgA及IgM存在。3
It has been recognized that there are many different types of immunodeficiency diseases with a qualitative and quantitative amount, but only 2 cases have been reported in the past in patients with specific humoral antibody deficiencies associated with normal amounts of IgG, IgA, IgM and IgE. This article describes a case of recurrent respiratory tract infection prompted immunodeficiency disease patients. Their cellular and humoral immune components and histology of lymph nodes were normal, but there was a selective defect of specific humoral immunity after antigen challenge. Case: Children with full-term follow-up, normal mother during pregnancy, there is no family history of abnormal sensitivity to infection. 13 months due to repeated nasal cold runny nose admission. Serum IgG at admission was 870 mg%, with IgA and IgM present. 3