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目的评价小剂量依托咪酯伍用丙泊酚和芬太尼无痛人流镇痛效果及安全性。方法 120例自愿接受无痛人流术的患者,随机分为Ⅰ组和Ⅱ组,各60例。两组:麻醉诱导前2 min先给芬太尼1μg/kg,1%丙泊酚静脉推注至患者角膜反射消失,Ⅰ组患者停止注药且手术开始,术中体动追加1%丙泊酚;Ⅱ组患者静脉注射依托咪酯0.1 mg/kg手术开始,术中体动追加1%丙泊酚。结果Ⅱ组丙泊酚总用量明显减少,血液流变学较Ⅰ组稳定。体动与Ⅰ组相比差异有统计学意义(P<0.05)。两组清醒时间、离院时间差异无统计学意义(P>0.05)。结论小剂量依托咪酯伍用丙泊酚和芬太尼用于人工流产术,麻醉镇痛效果好,是一种安全、较合理的方法。
Objective To evaluate the analgesic efficacy and safety of low dose etomidate with propofol and fentanyl in painless patients. Methods A total of 120 patients with painless abortion were randomly divided into group Ⅰ and group Ⅱ, 60 cases each. Two groups: Fentanyl 1μg / kg and propofol 1% were injected intravenously 2 minutes before the induction of anesthesia. The corneal reflex of patients disappeared. The patients in Group Ⅰ stopped injection and the operation was started. During the operation, 1% Phenol; Group Ⅱ patients with intravenous etomidate 0.1 mg / kg surgery began, intraoperative physical activity added 1% propofol. Results The total dosage of propofol in group Ⅱ decreased obviously, and the blood rheology was more stable than that in group Ⅰ. There was significant difference between body movement and group Ⅰ (P <0.05). There was no significant difference between the two groups in awake time and departure time (P> 0.05). Conclusion Small dose of etomidate with propofol and fentanyl for artificial abortion, anesthesia analgesic effect is good, is a safe, more reasonable method.