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目的探讨麻醉意识深度指数(CSI)指导异丙酚用药的可行性。方法60例人流患者,随机分对照组、CSI目标控制组。两组在消毒皮肤前5min均给予芬太尼1μg/kg,开始手术前对照组推注异丙酚2mg/kg,约60s注射完毕,术中有无体动追加异丙酚0.5mg/kg;目标控制组用微量泵按1mg.kg-1.min-1速度泵注异丙酚至CSI下降至60,根据CSI是否在目标范围内调节泵速,有体动给予异丙酚20mg。结果目标控制的异丙酚总用量少于对照组、应答时间、睁眼时间、下床时间短于对照组,差异有统计学意义。结论CSI指导组麻醉诱导迅速而平稳、术后恢复快而完全,CSI对指导无痛人流中的异丙酚用药和麻醉精确调控有好的指导意义。
Objective To investigate the feasibility of anesthesia awareness depth index (CSI) guidance propofol medication. Methods Sixty patients were randomly divided into control group and CSI control group. Both groups were given fentanyl 1μg / kg 5 min before disinfection of the skin, and propofol 2mg / kg was injected into the control group before operation. About 60s injection was completed. No intraoperative propofol 0.5mg / kg was added. In the target control group, propofol was pumped at a rate of 1 mg.kg-1.min-1 to a drop of 60 with a micropump at a rate of 1 mg.kg-1.min-1. Depending on whether CSI was adjusting the pump speed within the target range, propofol 20 mg was given. Results The total amount of propofol controlled by the target was less than that of the control group. The response time, eyes open time, and bed ambulation time were shorter than those of the control group. The difference was statistically significant. CONCLUSION: The CSI-guided anesthesia induces rapid and stable anesthesia, and the postoperative recovery is quick and complete. CSI has a good guiding significance for guiding the pain-free flow of propofol and precise anesthesia regulation.