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应用不开刀手术的方法进行绝育,已有百余年的历史。多数的方法都是在子宫角部造成物理或化学性灼伤,进行形成局部的纤维化。二年前,陕西省西安市开始应用α-氰基丙烯酸正丁酯(504)进行输卵管粘堵绝育。以后,各地均有报告。自1972年12月我院开始应用α-氰基丙烯酸异丁酯(661)和阿的平注射液进行输卵管闭塞绝育术,至今已有二年多,共千余例。成功率为70～80％。但应用α-氰基丙烯酸异丁酯和阿的平所致绝育的机制尚不明确。本实验的目的在于探讨α-氰基丙烯酸异丁酯(661)和阿的平溶液对家兔子宫的作用。
Application of non-surgical approach to sterilization, has a hundred years of history. Most of the methods are to cause physical or chemical burns in the corner of the uterus, the formation of local fibrosis. Two years ago, Xi’an, Shaanxi Province began to use α-cyano-n-butyl acrylate (504) for tubal sticky sterilization. Later, reports were made everywhere. Since December 1972, our hospital began to apply the α-cyanoacrylate isobutyl ester (661) and A-Ping injection of tubal occlusion sterilization, has been more than two years, a total of more than a thousand cases. The success rate is 70 ~ 80%. However, the mechanism of application of isobutyrate of α-cyanoacrylate and azepine is not clear. The purpose of this experiment was to explore the effect of isobutyl α-cyanoacrylate (661) and alanine solution on rabbit uterus.