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肥大细胞介质在哮喘的发病中起着重要作用。但关于哮喘患者支气管粘膜中肥大细胞的数量存在有争议。本研究采用了统一的支气管刷检方法,采集标本,以评估过敏性哮喘,非过敏哮喘和非哮喘患者支气管粘膜中肥大细胞的状况。 对象和方法 研究对象为23例非吸烟者,年龄22～63岁。根据病史,过敏原皮肤挑刺试验,乙酰甲胆碱气道反应性测定分为4组;非过敏非哮喘组5例,有过敏无哮喘组5例,非过敏性哮喘组5例,过敏性哮喘组8例。 按美国胸腔协会哮喘患者纤支镜检查指南进行准
Mast cell media play an important role in the pathogenesis of asthma. However, the number of mast cells in the bronchial mucosa of asthmatic patients is controversial. In this study, a uniform bronchial brushing test was used to collect specimens for evaluation of mast cells in bronchial mucosa in allergic asthma, non-allergic asthma, and non-asthmatic patients. Subjects and methods of study of 23 non-smokers, aged 22 to 63 years. According to the history, allergen skin prick test, methacholine airway reactivity were divided into 4 groups; 5 cases of non-allergic non-asthmatic group, 5 cases of allergic asthma group, 5 cases of non-allergic asthma group, allergic asthma Group of 8 cases. According to the American Society of Thoracostomy bronchoscopy guidelines for asthma prospective