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血清中抗核抗体(antinuclear antibodies ANA)的存在,一般可考虑为系统性红斑狼疮(SLE)的一种确诊依据。本文报导10例具有SLE临床征候而检查ANA持续阴性患者。这组病人常出现落发、雷诺氏现象和再发性口腔溃疡。ANA阴性SLE似乎是一
The presence of serum antinuclear antibodies (ANAs) is generally considered a definitive basis for systemic lupus erythematosus (SLE). This article reports 10 cases with SLE clinical signs and check ANA persistent negative patients. This group of patients often have hair loss, Raynaud’s phenomenon and recurrent oral ulcers. ANA negative SLE seems to be one