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目的:探讨超声心动图技术对于患有新生儿常见疾病的新生儿左心功能评估作用。方法:采用回顾性分析法,选取2010年11月~2013年11月新生儿科足月顺产新生儿100例,其中低氧血症患儿70例,母亲患有妊娠期糖尿病22例,先天性甲状腺功能低下8例,同时选取同期产科健康、足月顺产新生儿100例进行对照。分别在多普勒组织成像法模式下测定两组新生儿的二尖瓣环收缩期运动速度(Sa)、舒张期早期/晚期运动速度(Ea、Aa)及舒张期早期/舒张期晚期运动速度比值(Ea/Aa)。在M超声心动图模式下测定左室短轴缩短率(LVFS)和左室射血分数(LVEF)。采取脉冲多普勒技术(PWD)测量二尖瓣口血流舒张早期及舒张晚期峰值速度(Em、Am)并计算Em/Am。测定两组新生儿的ICT(等容收缩期)+IRT(等容舒张期),ET(射血时间)并计算Tei指数。结果:患病组的Sa、Ea、及Ea/Aa均显著低于对照组,P<0.01,且患病组的Aa显著高于对照组,P<0.01;患病组的LVFS、LVEF、Em、Am和Em/Am均显著低于对照组,P<0.01。患病组的左心Tei指数大于正常组,P<0.01,(ICT+IRT)大于正常组,ET小于正常组,P<0.01。结论:患有新生儿常见疾病的新生儿左心收缩和舒张功能较正常新生儿显著下降,超声心动图技术可以敏感地反映新生儿左心功能异常变化。
Objective: To evaluate the echocardiographic evaluation of neonatal left ventricular function in neonates with common diseases. Methods: A retrospective analysis method was used to select 100 cases of full-term newborn infants born in November 2010 to November 2013. Among them, 70 cases were hypoxemia, mothers had gestational diabetes mellitus in 22 cases, congenital thyroid 8 cases of low function, at the same time select the same period obstetric health, 100 cases of full-term newborn born to control. Mitral annulus systolic velocity (Sa), early / late diastolic velocity (Ea, Aa), and early diastolic / diastolic velocity were measured in Doppler tissue imaging. Ratio (Ea / Aa). Left ventricular fractional shortening (LVFS) and left ventricular ejection fraction (LVEF) were measured in M echocardiography. Pulse wave Doppler technique (PWD) was used to measure the early diastolic and early diastolic peak velocities (Em, Am) of mitral orifice and calculate Em / Am. ICT (isovolumic systolic phase) + IRT (isovolumic diastolic phase) and ET (ejection time) in both groups were measured and the Tei index was calculated. Results: Sa, Ea and Ea / Aa in the diseased group were significantly lower than those in the control group, P <0.01, and the Aa of the diseased group was significantly higher than that of the control group, P <0.01; LVFS, LVEF, Em , Am and Em / Am were significantly lower than the control group, P <0.01. The Tei index of left heart in the diseased group was higher than that in the normal group, P <0.01, (ICT + IRT) was higher than that in the normal group, ET was smaller than the normal group, P <0.01. CONCLUSION: Left ventricular systolic and diastolic function in neonates with common diseases is significantly lower than that in normal neonates. Echocardiography can sensitively reflect left ventricular dysfunction in neonates.