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目的探讨多层螺旋CT灌注成像技术在急性胰腺炎(AP)中的诊断价值。方法65例临床上诊断为急性胰腺炎患者作为AP组,60例无胰腺疾病的患者作为正常组,两组患者均采用16层螺旋CT进行灌注扫描。应用Per-fusion-3软件包进行数据分析,分别计算血流量(BF)、血容量(BV)、对比剂峰值时间(TTP)和毛细血管表面通透性(PS)。结果①AP患者BF和BV明显下降,与正常组比较差异有统计学意义(P<0.05);两组TTP、PS值差异无统计学意义(P>0.05)。②MAP胰腺CT灌注参数与正常组比较,差异无统计学意义(P>0.05);SAP患者与MAP患者及正常组比较BF、BV下降明显,相比较差异有统计学意义(P<0.05);TTP、PS改变不明显,差异无统计学意义(P>0.05)。结论MSCT多层灌注扫描是诊断急性胰腺炎的简便、有效的方法,对于急性胰腺炎的诊断具有一定的提示意义。
Objective To investigate the diagnostic value of multi-slice spiral CT perfusion imaging in acute pancreatitis (AP). Methods Sixty-five patients with acute pancreatitis were selected as AP group and 60 patients without pancreatic disease as normal group. Twenty-six patients underwent perfusion scan with 16-slice spiral CT. Per-fusion-3 software package was used for data analysis and BF, BV, TTP and PS were calculated respectively. Results ① BF and BV in AP patients decreased significantly compared with those in normal controls (P <0.05). There was no significant difference in TTP and PS between the two groups (P> 0.05). There was no significant difference in CT perfusion parameters between MAP and pancreatic tissue (P> 0.05); BF and BV decreased significantly in SAP patients and MAP patients (P <0.05); TTP , PS did not change significantly, the difference was not statistically significant (P> 0.05). Conclusion MSCT multi-layer perfusion scanning is a simple and effective method for the diagnosis of acute pancreatitis, which has some implications for the diagnosis of acute pancreatitis.