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采用高效液相色谱法,以WH-C18为固定相,扑尔敏为内标,甲醇-0.005mol/L醋酸铵(pH4.7)为流动相,测定盐酸吗啉胍片剂的含量。方法简便、快速准确。平均回收率99.74%,RSD0.60%。
The contents of morpholine-guanidine hydrochloride tablets were determined by HPLC with WH-C18 as stationary phase and chlorpheniramine as internal standard. Methanol-0.005 mol / L ammonium acetate (pH 4.7) was used as mobile phase. Method is simple, fast and accurate. The average recovery was 99.74%, RSD0.60%.