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目的 探讨合并糖尿病的脑梗死患者血清中可溶性细胞间粘附分子 (sICAM - 1)的变化及临床意义。方法 采用双抗体 (ELISA)法测定了 5 0例合并糖尿病的脑梗死患者血清中sICAM - 1的含量 ,并与30例不合并糖尿病的脑梗死患者及正常人 30例比较。结果 合并糠尿病的脑梗死患者血清sICAM - 1的水平明显高于正常人组 (P <0 .0 1) ,也高于单纯脑梗死患者 (P <0 .0 5 )。结论 糖尿病病人sICAM - 1的表达增加
Objective To investigate the changes and clinical significance of serum soluble intercellular adhesion molecule (sICAM - 1) in patients with diabetes mellitus complicated with cerebral infarction. Methods Serum levels of sICAM - 1 in 50 patients with diabetes mellitus were measured by ELISA. The serum levels of sICAM - 1 were compared with those in 30 patients without cerebral infarction and with normal controls. Results The level of sICAM - 1 in patients with cerebral infarction complicated with diabetes mellitus was significantly higher than that in normal controls (P <0.01) and higher than those in patients with simple cerebral infarction (P <0.05). Conclusion The expression of sICAM - 1 in diabetic patients increased