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目的：探讨太原市中心医院静脉溶栓院内延迟时间及影响因素。方法收集太原市中心医院启动入院至溶栓时间（door to needle time, DNT）控制节点项目前、后两组在4.5 h内接受重组组织型纤溶酶原激活物（rt-PA)静脉溶栓治疗的急性缺血性卒中患者的临床资料，比较两组患者的基线特点，分析影响院内延迟时间的相关因素。结果入院至得到化验结果和影像学结果时间在两组患者间差异有统计学意义。入院至溶栓（DNT）时间控制节点项目后入院至溶栓较前显著缩短。结论影响太原市中心医院静脉溶栓院内延迟时间的主要因素是入院至得到化验结果和影像学结果时间。入院至溶栓时间控制节点项目可显著缩短DNT。“,”Objective To analyze the in-hospital delay in thrombolytic treatment for stroke and to identify the factors which acted on the in-hospital delay. Methods Ischemic stroke patients who were treated with recombinant tissue plasminogen activator within 4.5 hours from stroke onset were enrolled in the study. They were divided into two groups based on the time between they were at the door of the hospital and the needle time (DNT). Their respective baseline characteristics were analyzed for determining the factors associated with in-hospital delay. Results The time from the admission and the imaging and laboratory result obtained between the two groups carried a statistical difference. The DNT decreased significantly once the DNT control plan was implemented. Conclusion The main factor affecting in-hospital delay was the time between admission and the imaging and laboratory result obtained. Implementation of door to needle control plan is considered being effective in reducing the DNT.