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目的 :观察非酒精性脂肪肝患者红细胞容积分布密度变化 ,探讨其与非酒精性脂肪肝病情严重程度及预后的相关性。方法 :应用全自动血细胞分析仪测定红细胞容积分布密度 ( RDW) ,应用全自动生化仪测定丙氨酸氨基转移酶 ( ALT)、γ-谷氨酰转移酶 (γ- GGT) ,应用酶法测定甘油三酯 ( TG)、总胆固醇 ( Tch)、高密度脂蛋白胆固醇 ( HDL - c) ,肝脏 B超检查 ( SI=45 0 ,探头 3.5 MHu) ,并将脂肪肝组与健康对照组进行比较。结果 :非酒精性脂肪性肝炎组、单纯性脂肪肝组的 RDW明显高于健康组 ,且与 AL T、GGT呈明显正相关。结论 :RDW可作为判断脂肪肝病情预后和诊疗的辅助因子
Objective: To observe the changes of erythrocyte volume density in patients with non-alcoholic fatty liver and to explore its correlation with the severity and prognosis of non-alcoholic fatty liver disease. Methods: The hematocrit density (RDW) was measured by automatic hematology analyzer. The alanine aminotransferase (ALT) and γ-glutamyl transferase (γ-GGT) were detected by automatic biochemical analyzer. Triglyceride (TG), total cholesterol (Tch), high density lipoprotein cholesterol (HDL - c), liver B ultrasonic examination (SI = 45 0, probe 3.5 MHu), and compare fatty liver group with healthy control group . Results: RDW in non-alcoholic steatohepatitis group and simple steatohepatitis group were significantly higher than those in healthy group, and were positively correlated with ALT and GGT. Conclusion: RDW can be used as a cofactor to judge the prognosis and diagnosis and treatment of fatty liver disease