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产前测定胎儿成熟度并了解其宫内生长情况,是提高新生儿成活率的关键。已受到普遍重视。近15年来,由于生物化学和生物物理学的飞速发展,为胎儿监护提供了有利条件。现将主要方法分述如下。一、产前监护 (一)产前的生物化学测定 1.孕妇尿雌三醇(E_3)的测定:已广泛应用。妇女雌激素主要来源于卵巢和胎盘,少量来自肾上腺和睾丸,以雌三醇、雌酮、雌二醇形式出现,其中雌二醇的生物活性最强。正常妇女尿雌三醇:雌酮:雌二醇为3∶3∶1,孕妇则为30∶2∶1。
Prenatal determination of fetal maturity and understanding of intrauterine growth is to improve the survival rate of newborns. Has received universal attention. The past 15 years, due to the rapid development of biochemistry and biophysics, provided favorable conditions for fetal custody. Now the main method is as follows. First, prenatal care (a) prenatal biochemical 1. Pregnancy women urine estriol (E_3) determination: has been widely used. Women estrogen mainly from the ovaries and placenta, a small amount from the adrenal glands and testis, estriol, estrone, estradiol form, of which estradiol strongest biological activity. Urinary estriol: estrone: estradiol 3: 3: 1 for normal women, 30: 2: 1 for pregnant women.